Science

 

WHAT IS RESVERATROL?

Resveratrol (trans-3,5,4′-Trihydroxystilbene) belongs to a class of natural compounds called stilbenes. Resveratrol and other stilbenes are small molecules that are rapidly synthesized by plants in response to attacks by bacteria, fungi and predators. Stilbenes presently are the focus of numerous biomedical research studies. Compounds within this chemical class have exhibited a capability to support a healthy inflammatory response in humans and animals.

HOW DOES RESVERATROL WORK?

Resveratrol proactively supports a healthy inflammatory response in the body of humans and animals. 

RESVERASYN®—STABLE, BIOAVAILABLE 98% RESVERATROL

Petthrive products contain a proprietary form of resveratrol called Resverasyn®. This is composed of 98% pure resveratrol that has been micronized and encapsulated. Micronization reduces the particle to a size where it is easily absorbed by the body, and encapsulation provides a coating that both protects resveratrol from deterioration and increases the distribution of the molecule to tissues.

Resveratrol must be microencapsulated to guarantee maximum bioavailability. Without this process, resveratrol can be very unstable when exposed to light or oxygen and is rapidly metabolized and excreted before it can reach tissues for therapeutic effects.

Use of our microencapsulated resveratrol product, Resverasyn, ensures your dog will consistently receive bioavailable resveratrol. Petthrive products are safe for long-term, daily use. 

WHY IS Petthrive WITH RESVERASYN DIFFERENT?

Resverasyn is manufactured by first producing trans-resveratrol of minimum 98% purity level. Each production lot of our trans-resveratrol is analyzed via high performance liquid chromatography (HPLC) to ensure that the product meets our 98% purity specification before it is microencapsulated to become our proprietary product Resverasyn.

Micronization is a process that reduces the particle size of resveratrol so that its bioavailability is enhanced. Encapsulation is a process whereby resveratrol molecules are covered in a protective coating. This process protects resveratrol particles from deterioration with exposure to light. Encapsulation also contributes to the bioavailability of resveratrol by allowing more of the molecule to enter the bloodstream and to be transported throughout the body.

WHERE DO OTHER COMPANIES OBTAIN RESVERATROL?

Resveratrol typically is associated with grapes and red wine. However, the concentration of resveratrol in wine, grapes, grape skin extracts and grape seed extracts is extremely low. The primary commercial source of resveratrol is a shrub named Japanese Knotweed (Polygonum cuspidatum) that is native to Asia. This plant is cultivated in China. Chinese manufacturing firms extract resveratrol from the rhizomes (underground stems) of the shrub.

RESVERATROL IMPURITIES

Chinese manufacturing firms produce Knotweed extracts that have resveratrol concentrations ranging from 20% to 98%. The corresponding percentage of impurities in these resveratrol products ranges from 2% to 98%. One of the impurities in Knotweed-based resveratrol products is a compound called emodin. This impurity has caused serious gastrointestinal distress in many people that have used Knotweed-based resveratrol products. The questionable purity and safety of Chinese resveratrol products derived from Japanese Knotweed raises cause for concern.

Use Petthrive brand products with Resverasyn® and be certain that your dog is receiving consistent amounts of pure, bioavailable resveratrol.